Naturderm, a division of Tranzderm Solutions, develops proprietary systems that enhance the delivery of actives for the cosmetic and pharmaceutical industries. 

Proprietary, protein-based systems that encapsulate and deliver actives include the following:

  • Naturproz is a plant-based system.  Naturproz consists of biocompatible and U.S. FDA-approved protein, which has characteristics similar to skin protein.  Naturproz can be used to encapsulate large and small molecules, as well as hydrophobic and hydrophilic molecules, with high encapsulation efficiency.  Naturproz improves the dispersibility, stability, retention, and sustained release of actives. 
  • Naturmicz is a plant-based micelle system.  Naturmicz consists of biocompatible and U.S. FDA-approved protein, and polyethylene glycol, a U.S. FDA-approved polymer, which form self-assembled micelles in aqueous solutions.  Naturmicz can be used to encapsulate hydrophobic molecules with high encapsulation efficiency.  Naturmicz improves dispersibility, solubility, stability, penetration, and retention of actives.

 

Product Pipeline: 

Tranzderm Solutions has successfully encapsulated and delivered a number of actives in the skin, including lipophilic and hydrophilic molecules, anti-cancer molecules such as 5-fluorouracil, and molecules such as curcumin.  Tranzderm Solutions’ proprietary systems have generated significant pre-clinical and scientific data that shows order-of-magnitude improvements in the encapsulation and delivery of multiple actives for cosmetic and pharmaceutical applications.

Tranzderm Solutions’ initial product focus is Vitamin A or retinol, which is an important cosmetic and pharmaceutical agent used to treat various skin conditions such as acne, photo-aging, and psoriasis.  The challenge with retinol is that it is unstable, with poor skin delivery characteristics such as penetration and retention, and significant irritation to the skin. 

Retizol is a proprietary formulation using the Naturproz and Naturmicz systems to enhance performance of retinol.  Retizol is soluble and dispersible in water, with enhanced solid and liquid state stability, skin penetration and sustained release, and most importantly, non-irritating to the skin.